Blog Archives

Congratulations to Dr. Min Dong for his Science paper!

This is about the mechanism of an unconventional radical SAM enzyme involved in diphthamide biosynthesis. http://science.sciencemag.org/content/359/6381/1247 Many thanks to our collaborators, Drs. Steve Ealick, Brian Hoffman, Jack Freed, Kyle Lancaster, and people in their lab for making the work possible

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Congrats to Hui and Xiaoyu!

Hui and Xiaoyu’s work on K-Ras has been published in eLife and ACS Central Science. Read the news story at Cornell Chronicle. http://chemistry.cornell.edu/news/research-probes-key-proteins-role-cancer-cell-growth  

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Congratulations to Zhewang for winning the Tunis Wentink Prize!

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Congratulations to Sush and Ornella on their PNAS paper!

The paper showed that SIRT5 is important for heart metabolism and function. Read the PNAS article or the Cornell Chronicle Story

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Zhen’s finding that DNA activates SIRT7 is published at ACS Chem. Biol.

See the article at ACS Chem. Biol.

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Our SIRT2 inhibitor work is published in Cancer Cell!

See theĀ  Cancer Cell article and the Cornell Chronicle story.  

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Our improved high-throughput assay for SIRT1, SIRT2, and SIRT3 is published in Org. Biomol. Chem.

See the OBC article online.

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Zhewang’s paper published in JACS

Congratulations to Zhewang! His paper, “Dph7 catalyzes a previously unknown demethylation step in diphthamide biosynthesis”, is published in JACS. This paper discovers the molecular function of Dph7 in diphthamide biosynthesis and provides a revised diphthamide biosynthesis pathway.

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Jing and Bin’s paper published in Org. Biomol. Chem.

Congratulations to Jing and Bin! Their paper, “A fluorogenic assay for screening Sirt6 modulators”, is published in Org. Biomol. Chem.

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